Critères d'inclusion : - Male or female who had first breast cancer surgery, regardless of the type of surgery
- Age ≥ 18 years
- Healthy, non-irritated skin on painful areas to treat
- During the inclusion visit to M4 post surgery, neuropathic pain of the breast and / or axillary area corresponding to inter-brachial neuralgia with a DN4≥4 score.
- Obtaining the signed written consent of the patient
- Major patient affiliated to a social security scheme
Critères de non-inclusion : - Contraindications specific to the treatments studied : capsaicine and pregabalin
- Diabetic patient
- Previous treatment with capsaicin or pregabalin
- Opioid treatment> 80 mg / day (oral morphine equivalent) in progress- Topical treatment of pain between surgery and inclusion visit
- Uncontrolled hypertension (systolic blood pressure ≥ 180 mmHg or diastolic blood pressure ≥ 90 mmHg) or recent history (<3 months) of cardiovascular events (stroke, heart attack, pulmonary embolism)
- Creatinine clearance (CLcr) <60mL / min according to the Cockcroft-Gault formula
- Pregnant woman, likely to be pregnant or breastfeeding
- Persons deprived of their liberty or guardianship (including curators),
- Impossibility of submitting to the medical follow-up of the test for geographical, social or psychological reasons